The data available to astronomers is growing exponentially. Large new instruments and surveys are generating ever-larger data sets, which are all becoming publically available. Many new observations are compared to and interpreted through new supercomputer simulations, which also produce massive data outputs. It is increasingly important to know how to deal effectively with this data avalanche. The objective of the 2012 UC-HiPACC Astro-Computing Summer School on AstroInformatics is to train the next generation of researchers in how to bring astronomical observations and simulations to a common framework, how to deal with the big data challenge, and more generally how to exploit the power of current and coming generations of supercomputers. The director will be Prof. Alex Szalay (Johns Hopkins University), and the other members of the organizing committee are Prof. Michael Norman (UCSD), director of the San Diego Supercomputer Center (SDSC), and Prof. Joel Primack (UCSC), director of the University of Cali